Cambridge Healthtech Institute’s 5th Annual

RNA-Modulating Small Molecule Drugs

Novel Approaches to Target RNA Structure, Binding, Interactions, and Function

April 3-4, 2024

With an increased understanding of diverse RNA moieties, their structure, function, and interactions, finding small molecules to target RNA is getting simpler. Small molecules offer enhanced stability, oral bioavailability, and better drug-like properties when compared to oligonucleotides. Hence, they are a more viable therapeutic option. However, identifying the right disease-causing RNA and evaluating the downstream physiological responses after small molecule modulation can be quite challenging. Challenges also exist in terms of optimizing the specificity, selectivity, and safety of these small molecules in vivo. Cambridge Healthtech Institute’s conference on RNA-Modulating Small Molecule Drugs will highlight some of the innovative approaches and technologies being used in this field.

Coverage will likely include:

Identifying and targeting the right RNA structures and mechanisms for therapeutic intervention
New functional and screening assays for quantifying small molecule-RNA binding and downstream function
Strategies for characterization and optimization of the RNA modulators, binders, and degraders
Targeting mRNA, miRNA, G-quadruplexes, and other RNA entities
Novel approaches for targeting and degrading RNA-modifying proteins and enzymes
Using AI and machine learning to design and predict RNA modulating activity

The deadline for priority consideration is September 15, 2023.

All proposals are subject to review by session chairpersons and/or the Scientific Advisory Committee to ensure the overall quality of the conference program. Additionally, as per Cambridge Healthtech Institute’s policy, a select number of vendors and consultants who provide products and services will be offered opportunities for podium presentation slots based on a variety of Corporate Sponsorships.

We hope you can join us for the 5 concurrent day-and-a-half conferences during each half of our 19th Annual Drug Discovery Chemistry event. Registering for this conference lets you also move back and forth among parallel programs to create your own agenda.

Opportunities for Participation: