Cambridge Healthtech Institute’s 7th Annual

RNA-Modulating Small Molecule Drugs

Novel Approaches to Target RNA Structure, Binding, Interactions, and Function

April 13, 2026


With an increased understanding of RNA structure, function, and interactions, there is greater interest in finding small molecules to target RNA for therapeutic intervention, as they offer enhanced stability, oral bioavailability, and better drug-like properties. However, identifying the right disease-causing RNA and evaluating the downstream physiological responses after small molecule binding can be quite challenging. Challenges also exist in terms of optimizing the specificity, selectivity, and safety of these small molecules in vivo. Cambridge Healthtech Institute’s symposium on RNA-Modulating Small Molecule Drugs will highlight some of the innovative approaches and technologies being used.

Coverage will likely include:

  • Identifying and targeting the right RNA structures and downstream mechanisms for therapeutic intervention
  • Screening tools for characterization and optimization of the RNA modulators, binders, and degraders
  • Developing new RNA splicing modulators
  • Targeting RNA-binding proteins
  • Designing RNA-targeting peptides
  • Covalent inhibitors and degraders for tackling mRNA targets
  • Using AI and machine learning to design and predict RNA modulating activity     

The deadline for priority consideration is September 30, 2025.

All proposals are subject to review by session chairpersons and/or the Scientific Advisory Committee to ensure the overall quality of the conference program. Additionally, as per Cambridge Healthtech Institute’s policy, a select number of vendors and consultants who provide products and services will be offered opportunities for podium presentation slots based on a variety of Corporate Sponsorships.

Opportunities for Participation:

For more details on the conference, please contact:
Tanuja Koppal, PhD
Senior Conference Director
Cambridge Healthtech Institute
Email: tkoppal@healthtech.com

For sponsorship information, please contact:
Kristin Skahan
Senior Business Development Manager
Cambridge Healthtech Institute
Phone: (+1) 781-972-5431
Email: kskahan@healthtech.com