Cambridge Healthtech Institute’s Inaugural

Oral & Macrocyclic Peptides: Discovery to Development - Part 2

Expanding the Frontier of Peptide Therapeutics

April 15-16, 2026


Cambridge Healthtech Institute’s Oral & Macrocyclic Peptides conference focuses on the design and development of peptide therapeutics that are either oral, membrane-permeable, or both! The ideal peptide therapeutic is orally bioavailable for patient convenience AND membrane-permeable so intracellular molecular complexes can be targeted. Macrocyclic peptides offer the potential for both properties in one molecule. The meeting’s expanded format (Part 1 and Part 2) not only reflects the excitement inspired by the success of GLP1-related anti-obesity peptide therapeutics but allows coverage of newer applications of macrocyclic peptides such as radioligands or drug conjugates. We also address formulation and translational considerations in appreciation of the growing impact of downstream chemistry on early-stage peptide therapeutic design. Join us to learn from and connect with leading discovery chemists in sharing insights and advances in the field of discovery peptide therapeutics.

Coverage will likely include:

Discovery & Design

  • Macrocyclic and constrained peptides
  • Cyclic peptides and unnatural amino acids
  • Oral cyclic peptides
  • Cell-penetrating peptides
  • Machine learning in peptide design
  • Late-stage functionalization strategies

Toward Oral Bioavailability

  • Designing for oral uptake
  • Peptide formulation and delivery

Therapeutic Modalities & Applications

  • GLP-1–inspired therapeutics beyond obesity/diabetes
  • Macrocyclic radioligands
  • Peptide drug conjugates
  • Peptides progressing in the clinic

The deadline for priority consideration is September 30, 2025.

All proposals are subject to review by session chairpersons and/or the Scientific Advisory Committee to ensure the overall quality of the conference program. Additionally, as per Cambridge Healthtech Institute’s policy, a select number of vendors and consultants who provide products and services will be offered opportunities for podium presentation slots based on a variety of Corporate Sponsorships.

Opportunities for Participation:

For more details on the conference, please contact:
Anjani Shah, PhD
Senior Conference Director
Cambridge Healthtech Institute
(+1) 781-247-6252
Email: ashah@healthtech.com

For sponsorship information, please contact:
Kristin Skahan
Senior Business Development Manager
Cambridge Healthtech Institute
Phone: (+1) 781-972-5431
Email: kskahan@healthtech.com