Cambridge Healthtech Institute’s 15th Annual
Oral & Macrocyclic Peptides – Part 1
Advancing the Frontier of Peptide Therapeutics
April 20-21, 2027
Cambridge Healthtech Institute's Oral & Macrocyclic Peptides conferences (parts 1 & 2) are among the few peptide therapeutics conferences devoted to chemistry. The cornerstone of this two-part meeting is oral and/or macrocyclic peptide design and discovery, reflecting the next generation of peptide therapeutics and this conference's claim to fame as the industry's first macrocyclic-focused conference. However, peptide chemistry with broad peptide drug discovery and development implications, such as those spurred by the flurry of GLP1-related peptide activity and downstream peptide development, will also be considered because the industry's frontier of peptide chemistry is relatively new and the scientists as well as the molecules are advancing together. Join us for this recently expanded two-part program to share progress, challenges, and solutions among leading medicinal and drug development peptide chemists, who are often one and the same (unlike the case for small molecules).
Coverage will likely include:
- Cyclic peptide design or discovery
- Design strategies for cell-permeable macrocyclics
- Macrocyclic peptide discovery: Encoded libraries (mRNA and DNA)
- Peptidomimetics and/or incoporating unnatural amino acids
- Machine learning/AI for peptide design
- Using chemistry to improving a peptide’s oral intrinsic bioavailability
- Using formulation to increase a peptide’s oral bioavailability
- Case studies on peptides for intracellular protein-protein interactions (PPIs)
- Process and scale-up challenges: Moving from solid to liquid phase
- Peptide-drug conjugates
- Radioligand therapies (peptide-based)
The deadline for priority consideration is October 5, 2026.
All proposals are subject to review by session chairpersons and/or the Scientific Advisory Committee to ensure the overall quality of the conference program. Additionally, as per Cambridge Healthtech Institute’s policy, a select number of vendors and consultants who provide products and services will be offered opportunities for podium presentation slots based on a variety of Corporate Sponsorships.
Opportunities for Participation:
- To submit a podium presentation, please click here.
- To become a sponsor, click here.
- To present a poster, click here.