Cambridge Healthtech Institute’s Inaugural

Emerging Technologies for Discovery Chemistry

Covalent Approaches and New Biophysical Tools

April 15-16, 2025

CHI's Inaugural Emerging Technologies for Discovery Chemistry conference convenes medicinal, biophysical, and structural chemists to strategize and learn from one another about deploying the latest biophysical technologies for new small molecule drug-lead generation. Covalent strategies, cryoEM, and innovations in biophysical screening applications such as the use of Affinity-Selection Mass Spectrometry (AS-MS), will be the focus. Join us to learn about scientists continually adapting technologies to keep pace with drug discovery innovations such as Targeted-Protein Degradation (TPD) strategies, applications of proteomics and DNA-Encoded Libraries (DEL) for small molecule screening and cryoEM for the design of new chemical entities against membrane targets.

Coverage will likely include:

Covalent drug discovery approaches, especially for TPD
Innovations in biophysical tools (NMR, SPR and mass spectrometry, especially AS-MS)
CryoEM applications to membrane-protein targeted drug discovery
Small molecule hit-to-lead case studies of novel technology applications

The deadline for priority consideration is September 27, 2024.

All proposals are subject to review by session chairpersons and/or the Scientific Advisory Committee to ensure the overall quality of the conference program. Additionally, as per Cambridge Healthtech Institute’s policy, a select number of vendors and consultants who provide products and services will be offered opportunities for podium presentation slots based on a variety of Corporate Sponsorships.

Opportunities for Participation: