Cambridge Healthtech Institute’s 2nd Annual

Targeting Transcription Factors

Tools, Strategies, Modulators to Pursue Intrinsically Disordered Proteins

APRIL 1, 2024 | 1:00-5:00 PM

Transcription factors (TF) are proteins with DNA-binding domains that are involved in transcribing DNA into RNA. Transcription factors have been targeted in different ways—by modulating their binding, interactions, activity, or expression levels, to generate the desired biological outcomes. However, their lack of defined structure and binding pockets have made them inherently “difficult-to-target.” This symposium on Targeting Transcription Factors brings together scientists who are working on innovative chemistries and technologies to modulate these promising drug targets for therapeutic intervention.