Targeting Transcription Factors  Icon

Cambridge Healthtech Institute’s Inaugural

Targeting Transcription Factors

April 10, 2023 | 2:20PM-5:30PM PDT

 

Transcription factors are proteins with DNA-binding domains that are involved in transcribing DNA into RNA. They are key cell regulators and alterations in their structure, binding or activity are often found associated with many abnormalities in cellular function or disease. Transcription factors have been targeted in different ways, by modulating their binding, interactions, activity, or expression levels, to generate the desired biological outcomes. However, their lack of defined structure and binding pockets have made them somewhat “undruggable”. This symposium on Targeting Transcription Factors brings together scientists who are working on innovative chemistries and technologies to target different transcription factors for therapeutic intervention.

 

Coverage will likely include:

 

  • Progress in targeting transcription factors like myc, p53, STAT, TEAD, HIF, Nrf2, and more
  • Utilizing innovative technologies to modify transcription factor regulation
  • New chemical biology and protein degradation strategies for targeting transcription factors
  • Development of small molecule inhibitors and activators of transcription factor-driven pathways
  • Understanding the structural basis of transcription factor-related mechanisms
  • New screening platforms and models for identifying transcription factor modulators

 

The deadline for priority consideration is September 23, 2022.

 

All proposals are subject to review by session chairpersons and/or the Scientific Advisory Committee to ensure the overall quality of the conference program. Additionally, as per Cambridge Healthtech Institute’s policy, a select number of vendors and consultants who provide products and services will be offered opportunities for podium presentation slots based on a variety of Corporate Sponsorships.

 

We hope you can join us for the 2 concurrent afternoon symposia during the first day of our 18th Annual Drug Discovery Chemistry event. Add on to your registration and attend the main event starting the next day. With two sets of 5 parallel conferences, you can also move back and forth to create your own agenda.

 

Opportunities for Participation:

 

 

For more details on the conference, please contact:

Tanuja Koppal, PhD

Senior Conference Director

Cambridge Healthtech Institute

Email: tkoppal@healthtech.com

 

For sponsorship information, please contact:

Kristin Skahan

Senior Business Development Manager

Cambridge Healthtech Institute

Phone: (+1) 781-972-5431

Email: kskahan@healthtech.com