Cambridge Healthtech Institute’s 6th Annual
Next-Generation Induced Proximity Modulators
Innovative Chemistries and Assays for Driving Covalent and Proximity-Triggered Interactions
April 19, 2027
Chemically-induced proximity is an emerging strategy for developing new therapies, and covalent chemistries are often being leveraged to trigger proximity-driven degradation, stabilization, localization, folding, post-translational modifications (PTMs) or disruption of protein-protein interactions. Cambridge Healthtech Institute’s symposium on Next-Generation Induced Proximity Modulators brings together academic and industry scientists from medicinal chemistry, chemical biology, assay development, proteomics, and more to discuss innovative chemistries and technologies for leveraging proximity-driven therapeutic intervention. This symposium is a precursor to what will be discussed in the conferences on Degraders and Glues, and Protein-Protein Interactions that follow.
Coverage will likely include:
- Induced-proximity approaches to tackle difficult-to-drug targets for therapeutic interventions
- Utilizing innovative covalent chemistries and linker optimization for inducing proximity
- Developments in proximity-inducing modalities for degradation and non-degrader applications
- Use of proximity inducers for dissecting kinetics and mechanisms of binding and PTMs
- Proximity-induced protein and peptide therapeutics
- Advances in AI models and tools for predicting chemically-induced proximity
- Direct-to-biology and phenotype-first proximity-driven drug discovery
The deadline for priority consideration is October 5, 2026.
All proposals are subject to review by session chairpersons and/or the Scientific Advisory Committee to ensure the overall quality of the conference program. Additionally, as per Cambridge Healthtech Institute’s policy, a select number of vendors and consultants who provide products and services will be offered opportunities for podium presentation slots based on a variety of Corporate Sponsorships.
Opportunities for Participation:
- To submit a podium presentation, please click here.
- To become a sponsor, click here.
- To present a poster, click here.