Cambridge Healthtech Institute’s 9th Annual
DNA-Encoded Libraries
A Small-Molecule Lead-Generation Technology with Expanding Possibilities
April 21-22, 2027
Over the past decade DNA-encoded libraries (DEL) have become a core component of pharmaceutical companies’ hit-finding campaigns for new therapeutics. DEL technology is also moving beyond traditional drug lead generation and making its mark in all facets of small-molecule drug discovery, even in peptide discovery. Why is DEL becoming indelible? Join us at CHI's 9th Annual DNA-Encoded Libraries conference to discuss with pioneers and more recent practitioners in the DEL field, the latest DEL successes, newer applications and "nitty-gritty" DELT innovations.
Coverage will likely include:
- DEL and D2B (direct-to-biology) applications
- Incorporating AI and machine learning
- DEL for degrader discovery
- Applying DEL to macrocyclic peptide discovery
- DEL for discovering covalent inhibitors
- Linkers and library-related insights
- New screening formats for DEL
- DEL methodology innovations (e.g., applications to GPCRs)
- DEL for judging target ligandability/druggability/scaffold hopping
- DEL for fragment screening
- Success stories: case studies of DEL hits-to-drug leads and beyond
The deadline for priority consideration is October 5, 2026.
All proposals are subject to review by session chairpersons and/or the Scientific Advisory Committee to ensure the overall quality of the conference program. Additionally, as per Cambridge Healthtech Institute’s policy, a select number of vendors and consultants who provide products and services will be offered opportunities for podium presentation slots based on a variety of Corporate Sponsorships.
Opportunities for Participation:
- To submit a podium presentation, please click here.
- To become a sponsor, click here.
- To present a poster, click here.